Article
High frequency of the Duffy-negative genotype and absence of Plasmodium vivax infections in Ghana.
Malaria journal - 17 Feb 2021
Brown Charles A, Pappoe-Ashong Prince J, Duah Nancy, Ghansah Anita, Asmah Harry, Afari Edwin, Koram Kwadwo A
Abstract excerpt
BACKGROUND: Recent studies from different malaria-endemic regions including western Africa have now shown that Plasmodium vivax can infect red blood cells (RBCs) and cause clinical disease in Duffy-negative people, though the Duffy-negative phenotype was thought to confer complete refractoriness against blood invasion with P. vivax. The actual prevalence of P. vivax in local populations in Ghana is unknown and...
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