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Article

High frequency of the Duffy-negative genotype and absence of Plasmodium vivax infections in Ghana.

Malaria journal - 17 Feb 2021

Brown Charles A, Pappoe-Ashong Prince J, Duah Nancy, Ghansah Anita, Asmah Harry, Afari Edwin, Koram Kwadwo A

Abstract excerpt

BACKGROUND: Recent studies from different malaria-endemic regions including western Africa have now shown that Plasmodium vivax can infect red blood cells (RBCs) and cause clinical disease in Duffy-negative people, though the Duffy-negative phenotype was thought to confer complete refractoriness against blood invasion with P. vivax. The actual prevalence of P. vivax in local populations in Ghana is unknown and...

Topics

Duffy Blood-Group System
Gene Frequency
Genotype
Ghana
Malaria, Vivax
Plasmodium vivax
Prevalence

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33596926
DOI: 10.1186/s12936-021-03618-0
PMCID: PMC7888148

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-33596926-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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