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Article

Reduced Plasmodium vivax erythrocyte infection in PNG Duffy-negative heterozygotes.

PloS one - 28 Mar 2007

Kasehagen Laurin J, Mueller Ivo, Kiniboro Benson, Bockarie Moses J, Reeder John C, Kazura James W, Kastens Will, McNamara David T, King Charles H, Whalen Christopher C, Zimmerman Peter A

Abstract excerpt

BACKGROUND: Erythrocyte Duffy blood group negativity reaches fixation in African populations where Plasmodium vivax (Pv) is uncommon. While it is known that Duffy-negative individuals are highly resistant to Pv erythrocyte infection, little is known regarding Pv susceptibility among heterozygous carriers of a Duffy-negative allele (+/-). Our limited knowledge of the selective advantages or disadvantages...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17389925
DOI: 10.1371/journal.pone.0000336
PMCID: PMC1829178

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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