Article
G1-like M and PB2 genes are preferentially incorporated into H7N9 progeny virions during genetic reassortment.
BMC veterinary research - 15 Feb 2021
Li Xiuli, Gu Min, Wang Xiaoquan, Gao Ruyi, Bu Xinxin, Hao Xiaoli, Ma Jing, Hu Jiao, Hu Shunlin, Liu Xiaowen, Chen Sujuan, Peng Daxin, Jiao Xinan, Liu Xiufan
Abstract excerpt
BACKGROUND: Genotype S H9N2 viruses have become predominant in poultry in China since 2010. These viruses frequently donate their whole internal gene segments to other emerging influenza A subtypes such as the novel H7N9, H5N6, and H10N8 viruses. We recently reported that the PB2 and M genes of the genotype S H9N2 virus, which are derived from the G1-like virus, enhance the fitness of H5Nx and H7N9 avian...
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