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Sequential reassortments underlie diverse influenza H7N9 genotypes in China.

Cell host & microbe - 16 Oct 2013

Wu Aiping, Su Chunhu, Wang Dayan, Peng Yousong, Liu Mi, Hua Sha, Li Tianxian, Gao George F, Tang Hong, Chen Jianzhu, Liu Xiufan, Shu Yuelong, Peng Daxin, Jiang Taijiao

Abstract excerpt

Initial genetic characterizations have suggested that the influenza A (H7N9) viruses responsible for the current outbreak in China are novel reassortants. However, little is known about the pathways of their evolution and, in particular, the generation of diverse viral genotypes. Here we report an in-depth evolutionary analysis of whole-genome sequence data of 45 H7N9 and 42 H9N2 viruses isolated from humans,...

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PMID: 24055604
DOI: 10.1016/j.chom.2013.09.001

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