Article
Hepatocyte nuclear factor 1 beta: A perspective in cancer.
Cancer medicine - 1 Mar 2021
Chandra Shubhra, Srinivasan Srilakshmi, Batra Jyotsna
Abstract excerpt
Hepatocyte nuclear factor 1 beta (HNF1 β/B) exists as a homeobox transcription factor having a vital role in the embryonic development of organs mainly liver, kidney and pancreas. Initially described as a gene causing maturity-onset diabetes of the young (MODY), HNF1β expression deregulation and single nucleotide polymorphisms in HNF1β have now been associated with several tumours including endometrial, prostate,...
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