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DNA methylation markers have universal prognostic value for anal cancer risk in HIV‐negative and HIV‐positive individuals

12 Feb 2021

Abstract excerpt

Anal cancer has increasing incidence and is preceded by high-grade anal intraepithelial neoplasia (HGAIN; AIN2-3). Previously, we identified and validated several methylation markers for accurate detection of anal cancer and HGAIN with cancer risk in HIV-positive (HIV+) men who have sex with men (MSM). This study aimed to evaluate these markers in HIV-negative risk groups. A cross-sectional series of 176 tissue...

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PMID: 33580586
DOI: 10.1002/1878-0261.12926

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