Article
A rigorous exploration of anal HPV genotypes using a next-generation sequencing (NGS) approach in HIV-infected men who have sex with men at risk for developing anal cancer.
Cancer medicine - 1 Jan 2020
Piyathilake Chandrika J, Badiga Suguna, Kumar Ranjit, Crowley Michael R, Burkholder Greer A, Raper James L
Abstract excerpt
BACKGROUND: There are no HPV-based measures for managing anal cancer (AC) in HIV-infected (HIV+) men who have sex with men (MSM) because of the high positivity of high-risk (HR)-HPVs. As next-generation sequencing (NGS) is able to describe the composition of HPVs as percent (%) reads rather than positive vs negative results, we used NGS approach to detect HPVs in anal samples of HIV+ MSM to test its ability to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.