Article
Screening for HIV-associated anal cancer: correlation of HPV genotypes, p16, and E6 transcripts with anal pathology.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2009
Salit Irving E, Tinmouth Jill, Chong Sylvia, Raboud Janet, Diong Christina, Su DeSheng, Sano Marie, Lytwyn Alice, Chapman William, Mahony James
Abstract excerpt
BACKGROUND: HIV-positive men with a history of anal-receptive intercourse are at risk for anal cancer. We determined whether human papilloma virus (HPV) biomarkers were correlated with anal pathology in these men. METHODS: HPV genotype was determined by PCR/line blot assay. Real-time PCR assays w...
Topics
- AIDS-Related Opportunistic Infections
- Alphapapillomavirus
- Anus Neoplasms
- Carcinoma in Situ
- DNA, Viral
- Genes, p16
- Genotype
- HIV Seropositivity
- Homosexuality, Male
- Humans
- Male
- Oncogene Proteins, Viral
- Papillomavirus Infections