Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of UCP1 and UCP2 variants with diabetic retinopathy susceptibility in type-2 diabetes mellitus patients: a meta-analysis.

BMC ophthalmology - 12 Feb 2021

Liu Xujia, Jiang Zehua, Zhang Guihua, Ng Tsz Kin, Wu Zhenggen

Abstract excerpt

BACKGROUND: Genetic association of uncoupling proteins (UCPs) variants with the susceptibility of diabetic retinopathy (DR) in diabetes mellitus (DM) patients has been reported but with controversy. Here we aimed to conduct a meta-analysis to confirm the association of different UCPs variants with DR. METHODS: Three databases (Medline Ovid, Embase Ovid and CENTRAL) were applied in the literature search. Five...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetic Retinopathy

Share to Genetic Predisposition to Disease

Share to Odds Ratio

Share to Polymorphism, Single Nucleotide

Share to Uncoupling Protein 1

Share to Uncoupling Protein 2

Source

Open in PubMed Open full text

Identifiers

PMID: 33579234
DOI: 10.1186/s12886-021-01838-1
PMCID: PMC7881628

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of UCP1 and UCP2 variants with diabetic retinopathy susceptibility in type-2 diabetes mellitus patients: a meta-analysis.PMID 33579234Read ↗

Association of UCP1 and UCP2 Variants With Diabetic Retinopathy Susceptibility in Type-2 Diabetes Mellitus Patients: A Meta-analysisSemantic proximity Read ↗

Analysis of association between common variants of uncoupling proteins genes and diabetic retinopathy in a Chinese population.Semantic proximity Read ↗

Investigation of variants in UCP2 in Chinese type 2 diabetes and diabetic retinopathy.Semantic proximity Read ↗

Polymorphisms of the UCP2 gene are associated with proliferative diabetic retinopathy in patients with diabetes mellitus.Semantic proximity Read ↗

The gene polymorphisms of UCP1 but not PPAR γ and TCF7L2 are associated with diabetic retinopathy in Chinese type 2 diabetes mellitus cases.Semantic proximity Read ↗

Association of uncoupling protein-2 -866G/A and Ala55Val polymorphisms with susceptibility to type 2 diabetes mellitus: A meta-analysis of case-control studies.Semantic proximity Read ↗

Ethnicity Differences in the Association of UCP1-3826A/G, UCP2-866G/A and Ala55Val, and UCP3-55C/T Polymorphisms with Type 2 Diabetes Mellitus Susceptibility: An Updated Meta-Analysis.Semantic proximity Read ↗

Associations between UCP1 -3826A/G, UCP2 -866G/A, Ala55Val and Ins/Del, and UCP3 -55C/T polymorphisms and susceptibility to type 2 diabetes mellitus: case-control study and meta-analysis.Semantic proximity Read ↗

The UCP1 -3826A/G polymorphism is associated with diabetic retinopathy and increased UCP1 and MnSOD2 gene expression in human retina.Semantic proximity Read ↗

Associations between polymorphisms in the mitochondrial uncoupling proteins (UCPs) with T2DM.Semantic proximity Read ↗

The role of uncoupling protein 2 (UCP2) on the development of type 2 diabetes mellitus and its chronic complicationsSemantic proximity Read ↗

Functional polymorphisms of UCP2 and UCP3 are associated with a reduced prevalence of diabetic neuropathy in patients with type 1 diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.