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Article

Polymorphisms of the UCP2 gene are associated with proliferative diabetic retinopathy in patients with diabetes mellitus.

Clinical endocrinology - 1 May 2010

Crispim Daisy, Fagundes Nelson J R, dos Santos Kátia G, Rheinheimer Jakeline, Bouças Ana P, de Souza Bianca M, Macedo Gabriel S, Leiria Leonardo B, Gross Jorge L, Canani Luís H

Abstract excerpt

BACKGROUND AND OBJECTIVE: Uncoupling protein 2 (UCP2) plays a role in controlling reactive oxygen species (ROS) production by mitochondria. As ROS overproduction is related to diabetic retinopathy (DR), UCP2 gene polymorphisms might be involved in the development of this complication. We investig...

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Source

Identifiers

PMID: 19681913
DOI: 10.1111/j.1365-2265.2009.03684.x

Genes

UCP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19681913-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Polymorphisms of the UCP2 gene are associated with proliferative diabetic retinopathy in patients with diabetes mellitus.PMID 19681913Read ↗

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The gene polymorphisms of UCP1 but not PPAR γ and TCF7L2 are associated with diabetic retinopathy in Chinese type 2 diabetes mellitus cases.Semantic proximity Read ↗

Analysis of association between common variants of uncoupling proteins genes and diabetic retinopathy in a Chinese population.Semantic proximity Read ↗

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