Article
The gene polymorphisms of UCP1 but not PPAR γ and TCF7L2 are associated with diabetic retinopathy in Chinese type 2 diabetes mellitus cases.
Acta ophthalmologica - 1 May 2015
Zhang Yue, Meng Nana, Lv Zhiping, Li Hao, Qu Yi
Abstract excerpt
PURPOSE: This study was designed to investigate the association between the polymorphisms in three insulin resistance-related genes, uncoupling protein-1 (UCP1), peroxisome proliferator-activated receptor γ (PPARγ) and transcription factor 7-like 2 (TCF7L2) and the susceptibility to diabetic retinopathy (DR) in a Chinese type 2 diabetes mellitus (T2DM) cohort. METHODS: A total of 792 patients with T2DM were...
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