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Article

DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary.

Developmental biology - 1 Aug 2011

Krentz Anthony D, Murphy Mark W, Sarver Aaron L, Griswold Michael D, Bardwell Vivian J, Zarkower David

Abstract excerpt

Dmrt1 belongs to the DM domain gene family of conserved sexual regulators. In the mouse Dmrt1 is expressed in the genital ridge (the gonadal primordium) in both sexes and then becomes testis-specific shortly after sex determination. The essential role of DMRT1 in testicular differentiation is well established, and includes transcriptional repression of the meiotic inducer Stra8. However Dmrt1 mutant females are...

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Source

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Identifiers

PMID: 21621532
DOI: 10.1016/j.ydbio.2011.05.658
PMCID: PMC3131262

Genes

DMRT1
STRA8
SYCP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary.PMID 21621532Read ↗

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