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Targeted DNA methylation profiling reveals epigenetic signatures in peanut allergy

11 Feb 2021

Abstract excerpt

DNA methylation (DNAm) has been shown to play a role in mediating food allergy; however, the mechanism by which it does so is poorly understood. In this study, we used targeted next-generation bisulfite sequencing to evaluate DNAm levels in 125 targeted highly informative genomic regions containing 602 CpG sites on 70 immune-related genes to understand whether DNAm can differentiate peanut allergy (PA) versus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33571165
DOI: 10.1172/jci.insight.143058

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