Article
Biomarkers Associated with Organ-Specific Involvement in Juvenile Systemic Lupus Erythematosus.
International journal of molecular sciences - 16 Jul 2021
Greenan-Barrett James, Doolan Georgia, Shah Devina, Virdee Simrun, Robinson George A, Choida Varvara, Gak Nataliya, de Gruijter Nina, Rosser Elizabeth, Al-Obaidi Muthana, Leandro Maria, Zandi Michael S, Pepper Ruth J, Salama Alan, Jury Elizabeth C, Ciurtin Coziana
Abstract excerpt
Juvenile systemic lupus erythematosus (JSLE) is characterised by onset before 18 years of age and more severe disease phenotype, increased morbidity and mortality compared to adult-onset SLE. Management strategies in JSLE rely heavily on evidence derived from adult-onset SLE studies; therefore, identifying biomarkers associated with the disease pathogenesis and reflecting particularities of JSLE clinical...
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