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Article

Metabolomic approach to characterize the metabolic phenotypes and varied response to ouabain of diffuse large B-cell lymphoma cells.

Leukemia & lymphoma - 1 Jul 2021

Zheng Meihong, Zhou Xuan, Wang Qien, Chen Xin, Cao Bei, Li Juan

Abstract excerpt

Germinal center B-cell-like (GCB) and activated B-cell-like (ABC) subtype diffuse large B-cell lymphoma (DLBCL) showed differential prognosis. Our results suggested that ouabain induced stronger inhibition of growth in Su-DHL4 (GCB), and it triggered obvious apoptosis in Su-DHL4 rather than in OCI-Ly3 (ABC). Two subtype cell lines also showed distinct metabolic phenotypes involving remarkable enrichment of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33565347
DOI: 10.1080/10428194.2021.1881513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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