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Article

Prognostic impact of B-vitamins involved in one-carbon metabolism in patients with diffuse large B-cell lymphoma.

Hematological oncology - 1 Oct 2020

Cao Yiwen, Chen Peizhan, Cai Minci, Shi Qing, Xu Pengpeng, Wang Li, He Yang, Wang Hui, Zhao Weili

Abstract excerpt

One-carbon metabolism (OCM) plays a pivotal role in both the stability and integrity of DNA and is mainly regulated by B-vitamins. This study aims to investigate the clinical relevance of B-vitamins and single nucleotide polymorphisms (SNPs) on OCM-related genes in diffuse large B-cell lymphoma (DLBCL). A total of 322 newly diagnosed DLBCL patients who received rituximab plus cyclophosphamide, doxorubicin,...

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Identifiers

PMID: 32469419
DOI: 10.1002/hon.2752

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