Article
Genetic predisposition to alcohol dependence: The combined role of polygenic risk to general psychopathology and to high alcohol consumption.
Drug and alcohol dependence - 1 Apr 2021
Facal Fernando, Flórez Gerardo, Blanco Vanessa, Rodríguez Julio, Pereiro César, Fernández José Manuel, Fariñas Emilio, Estévez Valentín, Gómez-Trigo Jesús, Gurriarán Xaquín, Sáiz Pilar, Vázquez Fernando Lino, Arrojo Manuel, Costas Javier
Abstract excerpt
BACKGROUND: High alcohol consumption and alcohol dependence are only partly genetically correlated and they differ considerably in their correlations with other traits. The existence of genetic correlation among alcohol dependence and psychiatric disorders may be attributed to the presence of a general psychopathology factor, the p factor. This study investigates the relationship of polygenic risk to general...
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