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Article

Human gut mycobiota tune immunity via CARD9-dependent induction of anti-fungal IgG antibodies.

Cell - 18 Feb 2021

Doron Itai, Leonardi Irina, Li Xin V, Fiers William D, Semon Alexa, Bialt-DeCelie Meghan, Migaud Mélanie, Gao Iris H, Lin Woan-Yu, Kusakabe Takato, Puel Anne, Iliev Iliyan D

Abstract excerpt

Antibodies mediate natural and vaccine-induced immunity against viral and bacterial pathogens, whereas fungi represent a widespread kingdom of pathogenic species for which neither vaccine nor neutralizing antibody therapies are clinically available. Here, using a multi-kingdom antibody profiling (multiKAP) approach, we explore the human antibody repertoires against gut commensal fungi (mycobiota). We identify...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33548172
DOI: 10.1016/j.cell.2021.01.016
PMCID: PMC7936855

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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