Article
A framework for exploring functional variability in olfactory receptor genes.
PloS one - 1 Aug 2007
Man Orna, Willhite David C, Crasto Chiquito J, Shepherd Gordon M, Gilad Yoav
Abstract excerpt
BACKGROUND: Olfactory receptors (ORs) are the largest gene family in mammalian genomes. Since nearly all OR genes are orphan receptors, inference of functional similarity or differences between odorant receptors typically relies on sequence comparisons. Based on the alignment of entire coding region sequence, OR genes are classified into families and subfamilies, a classification that is believed to be a proxy...
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