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Article

NMR spectroscopy captures the essential role of dynamics in regulating biomolecular function.

Cell - 4 Feb 2021

Alderson T Reid, Kay Lewis E

Abstract excerpt

Biomolecules are in constant motion. To understand how they function, and why malfunctions can cause disease, it is necessary to describe their three-dimensional structures in terms of dynamic conformational ensembles. Here, we demonstrate how nuclear magnetic resonance (NMR) spectroscopy provides an essential, dynamic view of structural biology that captures biomolecular motions at atomic resolution. We focus on...

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PMID: 33545034
DOI: 10.1016/j.cell.2020.12.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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