Article
Prognostic value of integrated cytogenetic, somatic variation, and copy number variation analyses in Korean patients with newly diagnosed multiple myeloma.
PloS one - 1 Jan 2021
Lee Nuri, Kim Sung-Min, Lee Youngeun, Jeong Dajeong, Yun Jiwon, Ryu Sohee, Yoon Sung-Soo, Ahn Yong-Oon, Hwang Sang Mee, Lee Dong Soon
Abstract excerpt
BACKGROUND: To investigate the prognostic value of gene variants and copy number variations (CNVs) in patients with newly diagnosed multiple myeloma (NDMM), an integrative genomic analysis was performed. METHODS: Sixty-seven patients with NDMM exhibiting more than 60% plasma cells in the bone marrow aspirate were enrolled in the study. Whole-exome sequencing was conducted on bone marrow nucleated cells. Mutation...
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