Article
Fabrication and assessment of chondroitin sulfate-modified collagen nanofibers for small-diameter vascular tissue engineering applications.
Carbohydrate polymers - 1 Apr 2021
Jia Weibin, Li Min, Liu Liling, Zhou Hang, Liu Xiankun, Gu Guofeng, Xiao Min, Chen Zonggang
Abstract excerpt
Chondroitin sulfate (ChS) has shown promising results in promoting cell proliferation and antithrombogenic activity. To engineered develop a dual-function vascular scaffold with antithrombosis and endothelialization, ChS was tethered to collagen to accelerate the growth of endothelial cells and prevent platelet activation. First, ChS was used to conjugate with collagen to generate glycosylated products (ChS-COL)...
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