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Enhanced proliferation and angiogenic phenotype of endothelial cells via negatively-charged alginate and chondroitin sulfate microsphere hydrogels.

Biomedical materials (Bristol, England) - 18 Feb 2021

Xiong Xiong, Xiao Wen, Zhou Sijie, Cui Rongwei, Xu Hockin H K, Qu Shuxin

Abstract excerpt

Sodium alginate-based hydrogel was the one of the most used polymers for cell delivery. However, the adsorption of extracellular matrix and proteins was inhibited due to the formation of a hydrated surface layer of these hydrogels. In this study, a novel cell delivery system, negatively-charged alginate and chondroitin sulfate microsphere hydrogel (nCACSMH), was fabricated with excellent permeability and...

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Identifiers

PMID: 33412523
DOI: 10.1088/1748-605X/abd994

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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