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A single-dose mRNA vaccine provides a long-term protection for hACE2 transgenic mice from SARS-CoV-2

3 Feb 2021

Abstract excerpt

The rapid expansion of the COVID-19 pandemic has made the development of a SARS-CoV-2 vaccine a global health and economic priority. Taking advantage of versatility and rapid development, three SARS-CoV-2 mRNA vaccine candidates have entered clinical trials with a two-dose immunization regimen. However, the waning antibody response in convalescent patients after SARS-CoV-2 infection and the emergence of human...

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PMID: 33536425
DOI: 10.1038/s41467-021-21037-2

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