Article

Preclinical evaluation of a SARS-CoV-2 mRNA vaccine PTX-COVID19-B

2021-05-12

Abstract excerpt

Safe and effective vaccines are needed to end the COVID-19 pandemic caused by SARS-CoV-2. Here we report the preclinical development of a lipid nanoparticle (LNP) formulated SARS-CoV-2 mRNA vaccine, PTX-COVID19-B. PTX-COVID19-B was chosen among three candidates after the initial mouse vaccination results showed that it elicited the strongest neutralizing antibody response against SARS-CoV-2. Further tests in mice...

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Literature Corpus work: 4a3fa91b-5fcb-5a00-923b-b763798d9a3f
DOI: 10.1101/2021.05.11.443286

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