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The Angelina Jolie effect: Contralateral risk-reducing mastectomy trends in patients at increased risk of breast cancer.

Scientific reports - 2 Feb 2021

Basu Narendra Nath, Hodson James, Chatterjee Shaunak, Gandhi Ashu, Wisely Julie, Harvey James, Highton Lyndsey, Murphy John, Barnes Nicola, Johnson Richard, Barr Lester, Kirwan Cliona C, Howell Sacha, Baildam Andrew D, Howell Anthony, Evans D Gareth

Abstract excerpt

Contralateral risk-reducing mastectomy (CRRM) rates have tripled over the last 2 decades. Reasons for this are multi-factorial, with those harbouring a pathogenic variant in the BRCA1/2 gene having the greatest survival benefit. On May 14th, 2013, Angelina Jolie shared the news of her bilateral risk-reducing mastectomy (BRRM), on the basis of her BRCA1 pathogenic variant status. We evaluated the impact of this...

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Identifiers

PMID: 33531640
DOI: 10.1038/s41598-021-82654-x
PMCID: PMC7854742

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