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Article

Association of ADAM10 gene variants with sporadic Parkinson's disease in Chinese Han population.

The journal of gene medicine - 1 Mar 2021

Zhou Miaomiao, Lin Yuwan, Lu Lin, Zhang Zhiling, Guo Wenyuan, Peng Guoyou, Zhang Wenlong, Zhu Ziting, Wu Zhuohua, Mo Mingshu, Yang Xinling, Zhu Xiaoqin, Chen Chaojun, Chen Xiang, Xu Pingyi

Abstract excerpt

BACKGROUND: Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide. Genetic factors play important roles in PD risk. rs653765 and rs514049 of ADAM10 were reported to be associated with Alzheimer's disease (AD) in Caucasian population; however, the association of the two variants with PD in Chinese Han population remains unknown. The present investigation aimed to explore the...

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PMID: 33527480
DOI: 10.1002/jgm.3319

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