Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An elementary mathematical modeling of drug resistance in cancer.

Mathematical biosciences and engineering : MBE - 2 Dec 2020

Bao Kangbo

Abstract excerpt

Targeted therapy is one of the promising strategies for the treatment of cancer. However, resistance to anticancer drug strongly limits the long-term effectiveness of treatment, which is a major obstacle for successfully treating cancer. In this paper, we analyze a linear system of ordinary differential equations for cancer multi-drug resistance induced mainly by random genetic point mutation. We investigate that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Drug Resistance, Neoplasm
Share to Models, Theoretical

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Neoplasms

Source

Identifiers

PMID: 33525095
DOI: 10.3934/mbe.2021018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An elementary mathematical modeling of drug resistance in cancer.PMID 33525095Read ↗

Stochastic modeling of drug resistance in cancer.Semantic proximity Read ↗

Probability of resistance evolution for exponentially growing virus in the host.Semantic proximity Read ↗

Modeling multi-mutation and drug resistance: analysis of some case studies.Semantic proximity Read ↗

Mathematical Model of Intrinsic Drug Resistance in Lung Cancer.Semantic proximity Read ↗

Evolution of resistance during clonal expansion.Semantic proximity Read ↗

Drug resistance in cancer mechanisms and modelsSemantic proximity Read ↗

Drug resistance in cancer: Principles of emergence and preventionSemantic proximity Read ↗

Mathematical Approach to Differentiate Spontaneous and Induced Evolution to Drug Resistance During Cancer TreatmentSemantic proximity Read ↗

Modeling the Dynamics of Heterogeneity of Solid Tumors in Response to Chemotherapy.Semantic proximity Read ↗

Modeling the chemotherapy-induced selection of drug-resistant traits during tumor growth.Semantic proximity Read ↗

The Fitness Cost of Therapeutic Resistance in Cancer: A Systematic ReviewSemantic proximity Read ↗

Impact of Resistance on Therapeutic Design: A Moran Model of Cancer GrowthSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.