In vivo selection of highly metastatic human ovarian cancer sublines reveals role for AMIGO2 in intra-peritoneal metastatic regulation.

doi:10.1016/j.canlet.2021.01.024

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Article

In vivo selection of highly metastatic human ovarian cancer sublines reveals role for AMIGO2 in intra-peritoneal metastatic regulation.

Cancer letters - 10 Apr 2021

Liu Yueying, Yang Jing, Shi Zonggao, Tan Xuejuan, Jin Norman, O'Brien Catlin, Ott Connor, Grisoli Anna, Lee Eric, Volk Kelly, Conroy Meghan, Franz Emily, Bryant Annamarie, Campbell Leigh, Crowley Brian, Grisoli Stephen, Alexandrou Aris T, Li Chunyan, Harper Elizabeth I, Asem Marwa, Johnson Jeff, Leonard Annemarie, Santanello Katie, Klein Ashley, Wang Qingfei, Zhang Siyuan, Hilliard Tyvette S, Stack M Sharon

Abstract excerpt

The majority of women with ovarian cancer are diagnosed with metastatic disease, therefore elucidating molecular events that contribute to successful metastatic dissemination may identify additional targets for therapeutic intervention and thereby positively impact survival. Using two human high grade serous ovarian cancer cell lines with inactive TP53 and multiple rounds of serial in vivo passaging, we generated...

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Identifiers

PMID: 33524500
DOI: 10.1016/j.canlet.2021.01.024
PMCID: PMC7981259

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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