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Article

AMIGO2 accelerates tumor progression by inducing a cancer stem cell-like phenotype.

Scientific reports - 25 Sept 2025

Seong Hee Kyung, Osaki Mitsuhiko, Izutsu Runa, Jehung Jumond P, Sato Reo, Sasaki Ryo, Hamada Junichi, Yamamoto Atsushi, Takenaka Atsushi, Okada Futoshi

Abstract excerpt

Amphoterin-induced gene and open reading frame 2 (AMIGO2) was previously identified as a driver gene for liver metastasis. AMIGO2 has also been found to be a prognostic factor for cancer patients with a low frequency of spontaneous liver metastasis. Here, we investigated whether AMIGO2 expression affects the acquisition of cancer stem cell-like properties in cancer cells by using human gastric (MKN45) and colon...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40998908
DOI: 10.1038/s41598-025-18095-7
PMCID: PMC12464190

Genes

AMIGO2
DLD
CD44

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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AMIGO2 accelerates tumor progression by inducing a cancer stem cell-like phenotype.PMID 40998908Read ↗

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