Article
Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metabolic pathways.
Gut - 1 Dec 2021
Arnoriaga-Rodríguez María, Mayneris-Perxachs Jordi, Contreras-Rodríguez Oren, Burokas Aurelijus, Ortega-Sanchez Juan-Antonio, Blasco Gerard, Coll Claudia, Biarnés Carles, Castells-Nobau Anna, Puig Josep, Garre-Olmo Josep, Ramos Rafel, Pedraza Salvador, Brugada Ramon, Vilanova Joan C, Serena Joaquín, Barretina Jordi, Gich Jordi, Pérez-Brocal Vicente, Moya Andrés, Fernández-Real Xavier, Ramio-Torrentà Lluis, Pamplona Reinald, Sol Joaquim, Jové Mariona, Ricart Wifredo, Portero-Otin Manuel, Maldonado Rafael, Fernández-Real Jose Manuel
Abstract excerpt
BACKGROUND: Inhibitory control (IC) is critical to keep long-term goals in everyday life. Bidirectional relationships between IC deficits and obesity are behind unhealthy eating and physical exercise habits. METHODS: We studied gut microbiome composition and functionality, and plasma and faecal metabolomics in association with cognitive tests evaluating inhibitory control (Stroop test) and brain structure in a...
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