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Article

Utilization of Whole Exome Sequencing Data to Identify Clinically Relevant Pharmacogenomic Variants in Pediatric Inflammatory Bowel Disease.

Clinical and translational gastroenterology - 1 Dec 2020

Mulder Daniel J, Khalouei Sam, Warner Neil, Gonzaga-Jauregui Claudia, Church Peter C, Walters Thomas D, Ramani Arun K, Griffiths Anne M, Cohn Iris, Muise Aleixo M

Abstract excerpt

INTRODUCTION: We hypothesized that variants within clinically relevant pharmacogenes could be identified using a whole exome sequencing data set derived from a cohort of more than 1,000 patients with inflammatory bowel disease (IBD). METHODS: Pediatric patients diagnosed with IBD underwent whole exome sequencing. We selected 18 genes with supporting literature where specific exonic variants would influence...

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Identifiers

PMID: 33512800
DOI: 10.14309/ctg.0000000000000263
PMCID: PMC7710220

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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