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Is Whole Exome Sequencing Clinically Practical in the Management of Pediatric Crohn's Disease?

Gut and liver - 23 Nov 2015

Oh Seak Hee, Baek Jiwon, Kim Kyung Mo, Lee Eun-Ju, Jung Yusun, Lee Yeoun Joo, Jin Hyun-Seung, Ye Byong Duk, Yang Suk-Kyun, Lee Jong-Keuk, Seo Eul-Ju, Lim Hyun Taek, Lee Inchul, Song Kyuyoung

Abstract excerpt

BACKGROUND/AIMS: The aim of this study was to identify the profile of rare variants associated with Crohn's disease (CD) using whole exome sequencing (WES) analysis of Korean children with CD and to evaluate whether genetic profiles could provide information during medical decision making. METHODS: DNA samples from 18 control individuals and 22 patients with infantile, very-early and early onset CD of severe...

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Identifiers

PMID: 26503572
DOI: 10.5009/gnl15176
PMCID: PMC4625707

Genes

XIAP

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