Article
Genetic predisposition to prostate cancer: an update.
Familial cancer - 1 Jan 2022
Ni Raghallaigh Holly, Eeles Rosalind
Abstract excerpt
Improvements in DNA sequencing technology and discoveries made by large scale genome-wide association studies have led to enormous insight into the role of genetic variation in prostate cancer risk. High-risk prostate cancer risk predisposition genes exist in addition to common germline variants conferring low-moderate risk, which together account for over a third of familial prostate cancer risk. Identifying men...
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