Article
Prostate Cancer Predisposition.
The Urologic clinics of North America - 1 Aug 2021
Bhanji Yasin, Isaacs William B, Xu Jianfeng, Cooney Kathleen A
Abstract excerpt
The identification and characterization of alterations in prostate cancer (PCa)-predisposing genes can help to inform screening strategies in undiagnosed men and treatment options in men in both the clinically localized and in the metastatic setting. This review provides an overview of the genetic basis underlying hereditary predisposition to PCa, the current role of genetics and PCa risk assessment, and how...
Topics
- Age Factors
- Biomarkers, Tumor
- Disease Progression
- Genetic Predisposition to Disease
- Genetic Testing
- Germ-Line Mutation
- Humans
- Male
- Polymorphism, Single Nucleotide
- Prostatic Neoplasms
- Risk Factors