Article
The impact of molecular profile on the lymphatic spread pattern in stage III colon cancer.
Cancer science - 1 Apr 2021
Song Jihyung, Kataoka Kozo, Yamada Takeshi, Shiozawa Manabu, Sonoyama Tomohiro, Beppu Naohito, Ueda Koji, Kuriyama Sho, Kanazawa Akiyoshi, Ikeda Masataka, Ceelen Wim
Abstract excerpt
The anatomical spread of lymph node (LN) metastasis is of practical importance in the surgical management of colon cancer (CC). We examined the effect of KRAS, BRAF, and microsatellite instability (MSI) on LN count and anatomical spread pattern in stage III CC. We determined KRAS, BRAF, and MSI status from stage III CC patients. Biomarker status was correlated with LN count and anatomical spread pattern, which...
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