Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Metastatic Pattern of Stage IV Colorectal Cancer with High-Frequency Microsatellite Instability as a Prognostic Factor.

Anticancer research - 1 Jan 2017

Fujiyoshi Kenji, Yamamoto Gou, Takenoya Takashi, Takahashi Akemi, Arai Yoshiko, Yamada Mina, Kakuta Miho, Yamaguchi Kensei, Akagi Yoshito, Nishimura Yoji, Sakamoto Hirohiko, Akagi Kiwamu

Abstract excerpt

BACKGROUND: A recent clinical trial on the immune check-point inhibitor pembrolizumab demonstrated that microsatellite instability (MSI) is a good biomarker for response to this inhibitor. However, clinicopathological features of advanced colorectal cancer (CRC) with high-frequency MSI (MSI-H) are unclear. PATIENTS AND METHODS: A total of 2,439 surgically resected CRC tissues were analyzed for MSI status, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to GTP Phosphohydrolases
Share to Liver Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lymphatic Metastasis

Share to Microsatellite Instability

Share to MutL Protein Homolog 1

Share to Peritoneal Neoplasms

Share to Proto-Oncogene Proteins B-raf

Share to Proto-Oncogene Proteins p21(ras)

Source

Identifiers

PMID: 28011498
DOI: 10.21873/anticanres.11313

Genes

BRAF
KRAS
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Metastatic Pattern of Stage IV Colorectal Cancer with High-Frequency Microsatellite Instability as a Prognostic Factor.PMID 28011498Read ↗

Outcomes of Chemotherapy for Microsatellite Instable–High Metastatic Colorectal CancersSemantic proximity Read ↗

Molecular and prognostic heterogeneity of microsatellite-unstable colorectal cancer.Semantic proximity Read ↗

Microsatellite Phenotype as a Guide for Immunotherapy in Colorectal Cancer: Current Status and Future Perspectives.Semantic proximity Read ↗

Effects of microsatellite instability on recurrence patterns and outcomes in colorectal cancersSemantic proximity Read ↗

Multicenter retrospective analysis of metastatic colorectal cancer (CRC) with high-level microsatellite instability (MSI-H)Semantic proximity Read ↗

Microsatellite Instability and KRAS Mutation in Stage IV Colorectal Cancer: Prevalence, Geographic Discrepancies, and Outcomes From the National Cancer Database.Semantic proximity Read ↗

Predictive model for high-frequency microsatellite instability in colorectal cancer patients over 50 years of age.Semantic proximity Read ↗

Colorectal cancer with BRAF V600E mutation: Trends in immune checkpoint inhibitor treatment.Semantic proximity Read ↗

Clinical significance of microsatellite instability in colorectal cancer.Semantic proximity Read ↗

High microsatellite instability (MSI-H) colorectal carcinoma: a brief review of predictive biomarkers in the era of personalized medicineSemantic proximity Read ↗

Reduced Likelihood of Metastases in Patients with Microsatellite-Unstable Colorectal CancerSemantic proximity Read ↗

The distinct clinical trajectory, metastatic sites, and immunobiology of microsatellite-instability-high cancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.