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Article

Phenotyping placental oxygenation in Lgals1 deficient mice using 19F MRI.

Scientific reports - 22 Jan 2021

Boehm-Sturm Philipp, Mueller Susanne, Freitag Nancy, Borowski Sophia, Foddis Marco, Koch Stefan P, Temme Sebastian, Flögel Ulrich, Blois Sandra M

Abstract excerpt

Placental hypoperfusion and hypoxia are key drivers in complications during fetal development such as fetal growth restriction and preeclampsia. In order to study the mechanisms of disease in mouse models, the development of quantitative biomarkers of placental hypoxia is a prerequisite. The goal of this exploratory study was to establish a technique to noninvasively characterize placental partial pressure of...

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PMID: 33483548
DOI: 10.1038/s41598-020-80408-9
PMCID: PMC7822814

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