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Article

Essentiality of c-di-AMP in Bacillus subtilis: Bypassing mutations converge in potassium and glutamate homeostasis.

PLoS genetics - 1 Jan 2021

Krüger Larissa, Herzberg Christina, Rath Hermann, Pedreira Tiago, Ischebeck Till, Poehlein Anja, Gundlach Jan, Daniel Rolf, Völker Uwe, Mäder Ulrike, Stülke Jörg

Abstract excerpt

In order to adjust to changing environmental conditions, bacteria use nucleotide second messengers to transduce external signals and translate them into a specific cellular response. Cyclic di-adenosine monophosphate (c-di-AMP) is the only known essential nucleotide second messenger. In addition to the well-established role of this second messenger in the control of potassium homeostasis, we observed that...

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Identifiers

PMID: 33481774
DOI: 10.1371/journal.pgen.1009092
PMCID: PMC7857571

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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