Asthma prescribing according to Arg16Gly beta-2 genotype: a randomised trial in adolescents.

doi:10.1183/13993003.04107-2020

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Asthma prescribing according to Arg16Gly beta-2 genotype: a randomised trial in adolescents.

The European respiratory journal - 1 Aug 2021

Ruffles Tom, Jones Christina J, Palmer Colin, Turner Steve, Grigg Jonathan, Tavendale Roger, Hogarth Fiona, Rauchhaus Petra, Pilvinyte Kristina, Hannah Romanie, Smith Helen, Littleford Roberta, Lipworth Brian, Mukhopadhyay Somnath

Abstract excerpt

INTRODUCTION: The A allele of rs1042713 (Arg16 amino acid) in the β2-adrenoreceptor is associated with poor response to long-acting β2-agonist (LABA) in young people with asthma. Our aim was to assess whether the prescribing of second-line controller with LABA or a leukotriene receptor antagonist according to Arg16Gly genotype would result in improvements in Pediatric Asthma-Related Quality of Life Questionnaire...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Administration, Inhalation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adolescent

Share to Adrenal Cortex Hormones

Share to Anti-Asthmatic Agents

Share to Asthma

Share to Child

Share to Drug Therapy, Combination

Share to England

Source

Open in PubMed

Identifiers

PMID: 33479111
DOI: 10.1183/13993003.04107-2020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Asthma prescribing according to Arg16Gly beta-2 genotype: a randomised trial in adolescents.PMID 33479111Read ↗

Tailored second-line therapy in asthmatic children with the Arg(16) genotype.Semantic proximity Read ↗

Arginine-16 beta2 adrenoceptor genotype predisposes to exacerbations in young asthmatics taking regular salmeterol.Semantic proximity Read ↗

Childhood asthma exacerbations and the Arg16 β2-receptor polymorphism: A meta-analysis stratified by treatment.Semantic proximity Read ↗

Genotype-driven asthma prescribing of inhaled corticosteroids and long-acting β2-agonist: A cost-effectiveness analysis.Semantic proximity Read ↗

Effect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial.Semantic proximity Read ↗

Pharmacogenetics of asthma: toward precision medicine.Semantic proximity Read ↗

Treatment response heterogeneity in asthma: the role of genetic variation.Semantic proximity Read ↗

Beta2-adrenoceptor polymorphisms predict response to beta2-agonists in children with acute asthma.Semantic proximity Read ↗

beta2 adrenoceptor Arg16Gly polymorphism, airway responsiveness, lung function and asthma in infants and children.Semantic proximity Read ↗

Arg16 ADRB2 genotype increases the risk of asthma exacerbation in children with a reported use of long-acting β2-agonists: results of the PACMAN cohort.Semantic proximity Read ↗

Beta 2 Adrenergic Receptor Genetic Polymorphisms in Bronchial Asthma: Relationship to Disease Risk, Severity, and Treatment Response.Semantic proximity Read ↗

ADRB2 haplotypes and asthma exacerbations in children and young adults: An individual participant data meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.