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BRCA1 and BRCA2 mutations in ovarian cancer patients from Belarus: update

21 Jan 2021

Abstract excerpt

BACKGROUND: Mutations in BRCA1 and BRCA2 are well-established risk factors for breast and ovarian cancer. In Central-Eastern European counties, the founder mutations in the BRCA1 are responsible for a significant proportion of ovarian cancer cases, however, regional differences in the frequencies of various mutations may exist. The spectrum and frequency of BRCA1/2 mutations between ovarian cancer patients have...

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PMID: 33478551
DOI: 10.1186/s13053-021-00169-y

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