Article
Drosophila Hox genes induce melanized pseudo-tumors when misexpressed in hemocytes.
Scientific reports - 19 Jan 2021
Ponrathnam Titus, Saini Ravina, Banu Sofia, Mishra Rakesh K
Abstract excerpt
Hox genes are early determinants of cell identity along the anterior-posterior body axis across bilaterians. Several late non-homeotic functions of Hox genes have emerged in a variety of processes involved in organogenesis in several organisms, including mammals. Several studies have reported the misexpression of Hox genes in a variety of malignancies including acute myeloid leukemia. The Hox genes Dfd, Ubx,...
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