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Characterization of an IncFIB/IncHI1B Plasmid Encoding Efflux Pump TMexCD1-TOprJ1 in a Clinical Tigecycline- and Carbapenem-Resistant Klebsiella pneumoniae Strain

20 Jan 2021

Abstract excerpt

A novel plasmid-encoded resistance-nodulation-division (RND) efflux pump, TMexCD1- TOprJ1, conferring resistance to multiple drugs, including tigecycline, has recently been identified in Klebsiella pneumoniae strains (1, 2).However, the gene cluster tmexCD1-toprJ1 was rarely identified in clinical Enterobacteriaceae isolates (1).Here, we report a novel plasmid from a clinical K. pneumoniae strain isolated in Hong...

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PMID: 33468479
DOI: 10.1128/aac.02340-20

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