Article
Smoking and stroke: A mendelian randomization study.
Annals of neurology - 1 Sept 2019
Larsson Susanna C, Burgess Stephen, Michaëlsson Karl
Abstract excerpt
We used the Mendelian randomization design to explore the potential causal association of smoking with ischemic stroke and intracerebral hemorrhage using summary statistics data for 34,217 ischemic stroke cases and 404,630 noncases, and 1,545 cases of intracerebral hemorrhage and 1,481 noncases. Genetic predisposition to smoking initiation (ever smoking regularly), based on up to 372 single-nucleotide...
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