Article
Genetic predisposition to smoking in relation to 14 cardiovascular diseases.
European heart journal - 14 Sept 2020
Larsson Susanna C, Mason Amy M, Bäck Magnus, Klarin Derek, Damrauer Scott M, Michaëlsson Karl, Burgess Stephen
Abstract excerpt
AIMS: The aim of this study was to use Mendelian randomization (MR) to determine the causality of the association between smoking and 14 different cardiovascular diseases (CVDs). METHODS AND RESULTS: Our primary genetic instrument comprised 361 single-nucleotide polymorphisms (SNPs) associated with smoking initiation (ever smoked regularly) at genome-wide significance. Data on the associations between the SNPs...
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