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Article

GRDN-1/Girdin regulates dendrite morphogenesis and cilium position in two specialized sensory neuron types in C. elegans.

Developmental biology - 1 Apr 2021

Nechipurenko Inna, Lavrentyeva Sofia, Sengupta Piali

Abstract excerpt

Primary cilia are located at the dendritic tips of sensory neurons and house the molecular machinery necessary for detection and transduction of sensory stimuli. The mechanisms that coordinate dendrite extension with cilium position during sensory neuron development are not well understood. Here, we show that GRDN-1, the Caenorhabditis elegans ortholog of the highly conserved scaffold and signaling protein...

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Identifiers

PMID: 33460640
DOI: 10.1016/j.ydbio.2020.12.022
PMCID: PMC7956162

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