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Article

ABCB1, ABCG2, ABCC1, ABCC2, and ABCC3 drug transporter polymorphisms and their impact on drug bioavailability: what is our current understanding?

Expert opinion on drug metabolism & toxicology - 1 Apr 2021

Bruckmueller Henrike, Cascorbi Ingolf

Abstract excerpt

INTRODUCTION: Interindividual differences in drug response are a frequent clinical challenge partly due to variation in pharmacokinetics. ATP-binding cassette (ABC) transporters are crucial determinants of drug disposition. They are subject of gene regulation and drug-interaction; however, it is still under debate to which extend genetic variants in these transporters contribute to interindividual variability of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33459081
DOI: 10.1080/17425255.2021.1876661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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