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Article

The distribution in native populations from Mexico and Central America of the C677T variant in the MTHFR gene.

American journal of human biology : the official journal of the Human Biology Council - 1 Nov 2021

Reyes Lucio, Godfrey David, Ming Li-June, MacLean Caroline, Gonzalez Francisco J, Madrigal Lorena

Abstract excerpt

OBJECTIVES: To explore evolutionary hypotheses for the high frequencies of a substitution in the methylenetetrahydrofolate reductase (MTHFR) gene, in Mexican and Central American Indigenous populations. MATERIALS AND METHODS: We obtained allele frequencies for the C677T variant in the MTHFR gene and ecological information for 37 indigenous samples from Mexico and Central America. We calculated Hardy-Weinberg...

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PMID: 33458918
DOI: 10.1002/ajhb.23567

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