Article
Genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) in ethnic populations in Texas; a report of a novel MTHFR polymorphic site, G1793A.
American journal of medical genetics - 15 Jan 2002
Rady Peter L, Szucs Sylvia, Grady James, Hudnall S David, Kellner Leonard H, Nitowsky Harold, Tyring Stephen K, Matalon Reuben K
Abstract excerpt
The importance of hyperhomocysteinemia, birth defects, and vascular diseases has been the subject of intense investigations. The polymorphic MTHFR mutations (C677T and A1298C) cause mild hyperhomocysteinemia, especially in homozygotes for C677T, but also in compound heterozygotes for C677T/A1298C. The subject of this report is the frequency of the polymorphic mutations in the MTHFR gene C677T, C1298A, and newly...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.