Article
A minimal physical model for curvotaxis driven by curved protein complexes at the cell's leading edge.
Proceedings of the National Academy of Sciences of the United States of America - 19 Mar 2024
Sadhu Raj Kumar, Luciano Marine, Xi Wang, Martinez-Torres Cristina, Schröder Marcel, Blum Christoph, Tarantola Marco, Villa Stefano, Penič Samo, Iglič Aleš, Beta Carsten, Steinbock Oliver, Bodenschatz Eberhard, Ladoux Benoît, Gabriele Sylvain, Gov Nir S
Abstract excerpt
Cells often migrate on curved surfaces inside the body, such as curved tissues, blood vessels, or highly curved protrusions of other cells. Recent in vitro experiments provide clear evidence that motile cells are affected by the curvature of the substrate on which they migrate, preferring certain curvatures to others, termed "curvotaxis." The origin and underlying mechanism that gives rise to this curvature...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.